Saquon Barkley #26 of the New York Giants runs the ball during the first quarter against the Dallas Cowboys at AT&T Stadium on Oct. 10, 2021 in Arlington, Texas.
New York Giants running back Saquon Barkley has been ruled out in the first half against the Dallas Cowboys with a left ankle injury.
The injury happened when Barkley stepped on Dallas cornerback Jourdan Lewis' foot on a play away from the ball. TV footage showed significant swelling on the ankle.
Watch NBC 5 free wherever you are
Barkley missed all but two games last year after tearing the anterior cruciate ligament in his right knee. The fourth-year back was coming off his first game of the season with more than 100 scrimmage yards.
Before the injury, Barkley carried twice for 9 yards.
Get top local stories in DFW delivered to you every morning with NBC DFW's News Headlines newsletter.