The eastbound lanes of Interstate 635 after Royal Lane and Miller Road were shut down after a fatal incident on Sunday night, police said.
The accident occurred shortly before 11:30 p.m. when a pedestrian was struck on the freeway.
The Dallas Police Department's accident investigators responded to the scene.
According to police, a woman was struck by multiple vehicles while she attempted to cross the freeway.
The freeway was fully cleared and reopened at approximately 5:15 a.m.