Researchers Want to Know If Inflammation is to Blame for Brain Fog

NBC Universal, Inc.

As we age, the chances increase that weโ€™ll have memory lapses, forgetfulness, and a decline in cognitive function. Research over the past few years suggests that inflammation plays a part. Now, researchers want to determine what role inflammation plays in memory problems in cancer patients.

Acute inflammation is easy to see โ€“ a cut, redness, or swelling. Itโ€™s the bodyโ€™s response to injury. But chronic inflammation is often invisible, with no telltale signs, yet, doctors say it can take a toll.

โ€œIt's always been thought that inflammation can potentially have a connection between cognitive changes, even in non-cancer patients,โ€ said Dr. Deena Mary Atieh Graham, a Medical Oncologist at the Hackensack University Medical Center.

Now, cancer researchers want to know what role chronic inflammation caused by physical or emotional stress can play on a patientโ€™s cognition. In a recent study, they took blood from 400 breast cancer survivors to measure their C-reactive protein or CRP levels.

โ€œThese inflammatory markers or proteins in your blood can be elevated when the body is under some form of stress,โ€ said Graham.

Graham and colleagues at Georgetown found that chronic inflammation may play a role in the development of cognitive problems. They say by identifying a scientific predictor for memory problems they can help patients prevent them.

โ€œI don't think it's gonna be a one-and-done, but I think this is a step,โ€ Graham adds.

Graham says the next step will be to identify interventions that can lower the inflammation. Graham says that might not be a medicine that patients can take but might involve lifestyle changes in combination with other therapies.

Contributors to this news report include: Cyndy McGrath, Producer; Kirk Manson, Videographer; Roque Correa, Editor.

Contact Us