• A recent monkeypox outbreak across the U.S., Europe, Australia and the Middle East has baffled health experts and is raising concerns of a wider outbreak.
• The majority of cases so far have spread through sex, with a particular concentration among gay and bisexual men. However, anyone could be at risk of catching monkeypox.
• Practicing good hygiene and safe sex are among some of the precautions you can take to reduce your risk of contracting the virus.

A recent monkeypox outbreak across the U.S., Europe, Australia and the Middle East has baffled health experts and is raising concerns of a wider outbreak.

As of Wednesday, there were 346 confirmed and suspected cases in 22 countries outside of Africa, where the virus is endemic, according to Our World in Data.

It marks the first known community spread of the virus. Before this outbreak, cases had been linked to travel to regions where the virus is endemic or imported animals carrying the virus.

The majority of new cases have spread through sex, with a particular concentration among men who have sex with other men. However, the World Health Organization has cautioned that anyone could be at risk of contracting the virus. Children, pregnant woman and the immunocompromised are considered particularly at risk.

"Anyone who has close contact with someone who is infectious is at risk," a release on the WHO's website said Wednesday.

Monkeypox is a rare disease caused by the monkeypox virus, part of the same family as smallpox, although typically less severe. Smallpox vaccinations have proven 85% effective against monkeypox.

The WHO said Monday that it was unlikely mass vaccinations would be required to combat the spike in cases. But, given the pace of the outbreak and the lack of clarity around its cause, the public health body urged people to practice good hygiene and safe sex to help control its spread.

Protecting yourself against monkeypox

While health experts agree the risks to the general public are low, there are several precautions you can take to reduce your risk of contracting the virus.

Recommendations from the U.S. Centers for Disease Control and Prevention, the U.K.'s National Health Service and WHO include:

• Avoid coming into contact with people recently diagnosed with the virus or those who may have been infected.

• Wear a face mask if you are in close contact with someone who has symptoms.

• Use condoms and keep an eye out for symptoms if you have recently changed sexual partners.

• Avoid coming into contact with animals that could be carrying the virus. This includes sick or dead animals and particularly those with a history of infection, such as monkeys, rodents and prairie dogs.

• Practice good hand hygiene, especially after coming into contact with infected — or suspected infected — animals or humans. For instance, wash your hands with soap and water or use an alcohol-based hand sanitizer.

• Use personal protective equipment when caring for patients with confirmed or suspected monkeypox infection.

• Only eat meat that has been cooked thoroughly.

Monkeypox can also be transmitted via surfaces and materials, so it's wise to avoid touching materials that have been in contact with a sick human or animal.

"This is a virus that is super stable outside the human host, so it can live on objects like blankets and things like that," Dr. Scott Gottlieb, a former FDA commissioner, said Monday.

"Good practice would be to regularly wash clothing and bedsheets at high temperature," Emmanuel Andre, professor at medicine at Belgium's Ku Leuven University, told CNBC on Wednesday.

However, he said he did not think it would be necessary for the general public to start avoiding public areas, taxis, shopping and hotels.

"The general population don't need to take many more precautions than we do in usual life," he said. "If people are in the high-risk population, where they are aware they are in a high-risk environment, then they should take extra precautions."

What to do if you catch monkeypox

If you suspect that you may have contracted monkeypox, you should isolate yourself from physical contact with others and seek medical advice immediately.

Initial symptoms of monkeypox include fever, headaches, muscle ache, swelling and backpain. Rashes and lesions then typically emerge on the face, hands, feet, eyes, mouth or genitals within one to five days. Those rashes turn into raised bumps and then blisters, which may fill with white fluid before breaking and scabbing over.

Many of the symptoms of the virus can be easily confused with other diseases, such as chickenpox, herpes or syphilis, however, so medical confirmation is important.

If you are diagnosed with monkeypox, you will need to isolate until the virus has passed. The illness is typically mild and most people recover within two to four weeks.

While medical advice currently varies across countries, the U.K.'s National Health Service notes that you may need to stay in a specialist hospital to prevent infection spreading to other people.

Disclosure: Scott Gottlieb is a CNBC contributor and is a member of the boards of Pfizer, genetic testing start-up Tempus, health-care tech company Aetion Inc. and biotech company Illumina. He also serves as co-chair of Norwegian Cruise Line Holdings' and Royal Caribbean's "Healthy Sail Panel."